A genome-wide linkage study of autism spectrum disorder and the broad autism phenotype in extended pedigrees
نویسندگان
چکیده
منابع مشابه
Genome-wide linkage analyses of two repetitive behavior phenotypes in Utah pedigrees with autism spectrum disorders
BACKGROUND It has been suggested that efforts to identify genetic risk markers of autism spectrum disorder (ASD) would benefit from the analysis of more narrowly defined ASD phenotypes. Previous research indicates that 'insistence on sameness' (IS) and 'repetitive sensory-motor actions' (RSMA) are two factors within the ASD 'repetitive and stereotyped behavior' domain. The primary aim of this s...
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Background: Autism Spectrum Disorder (ASD) is a complex developmental disorder characterized by repetitive and stereotypical patterns, and difficulties with social communication and interaction in early childhood. Motor development and dysfunction in children with ASD has been the subject of study in recent years and has attracted much of the attention of researchers. As motor dysfunctions can ...
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BACKGROUND Autism Spectrum Disorders (ASD) are phenotypically heterogeneous, characterized by impairments in the development of communication and social behaviour and the presence of repetitive behaviour and restricted interests. Dissecting the genetic complexity of ASD may require phenotypic data reflecting more detail than is offered by a categorical clinical diagnosis. Such data are availabl...
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The literature on international travellers with psychiatric disorders is limited. This perspective article highlights various travel-related aspects of autism spectrum disorder (ASD), including its aetiological association with maternal migration, the difficulties faced by long-term travelers with autistic children, and the facilitation of international travel for autistic individuals by the tr...
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Context—There now exist multiple reports of a constellation of language, personality, and socialbehavioral features present among relatives that mirror the symptom domains of autism, but much milder in expression. Studies of this ‘broad autism phenotype’ (BAP) may provide a potentially important, complementary approach for detecting the genes causing autism and defining associated neural circui...
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ژورنال
عنوان ژورنال: Journal of Neurodevelopmental Disorders
سال: 2018
ISSN: 1866-1947,1866-1955
DOI: 10.1186/s11689-018-9238-9